TAILEM BEND PHARMACY  
& KAROONDA PHARMACY DEPOT
 
Disease: Acne                         PREVIOUS PAGE                                    
ALTERNATIVE NAMES 
cystic acne; acne vulgaris; pimples 
 
DEFINITION 
An inflammatory skin condition characterized by superficial skin eruptions that are caused by plugging of the 
skin pores. 
 
CAUSES, INCIDENCE, AND RISK FACTORS 
Acne is most common in adolescent boys, but it can occur in both sexes and at all ages. There seems to be a 
familial tendency to develop acne. The condition usually begins at puberty and may continue for many years. 
Three out of four teenagers have acne to some extent, probably caused by hormonal changes that stimulate the 
sebaceous (oil producing) skin glands. Other hormonal changes, such as can occur with menstrual periods, 
pregnancy, use of birth control pills, or stress, also aggravate acne. 
Acne is caused when sebaceous glands within the hair follicles (pores) of the skin become plugged, because 
secretion occurs faster than the oil and skin cells can exit the follicle. The plug causes the follicle to bulge 
(causing whiteheads), and the top of the plug may darken (causing blackheads). If the plug causes the wall of the 
follicle to rupture, the oil, dead skin cells, and bacteria found normally on the surface of the skin can enter the 
skin and form small infected areas called pustules (also known as pimples or "zits"). 
If these infected areas are deep in the skin, they may enlarge to form cysts. A sebaceous cyst forms when the 
sebaceous gland continues to produce oil. Instead of rupturing the follicle wall, the follicle continues to enlarge 
and form a soft, pliable lump (known as a cyst) under the skin. The cyst is usually not painful or discolored 
unless it becomes infected. 
Acne is not caused by dirt or by masturbation or other activities, but dirt and oil on the face can aggravate the 
condition. Other factors that increase the chances of acne are hormonal changes, exposure to weather extremes, 
stress, oily skin, endocrine disorders, certain tumors, and the use of certain drugs (such as cortisone, testosterone
estrogen, and others). Acne is not contagious. 
 
PREVENTION 
The tendency to develop acne is inherited. Although acne cannot be prevented, careful cleanliness can help to 
lessen the effects. 
 
SYMPTOMS 
- skin rash or lesion on the face, truck (chest) neck, back, or other area 
- comedones (whiteheads or blackheads) 
- pustules 
- cysts 
- papules 
- nodules 
- redness (erythema) of the skin lesions or skin around a lesion 
- inflammation around the skin eruptions 
- crusting of skin eruptions 
- scarring of the skin 
 
SIGNS AND TESTS 
Diagnosis is primarily based on the appearance of the skin. No testing is usually required. 
 
TREATMENT 
Treatment is designed to prevent formation of new lesions and aid the healing of old lesions. 
Topical medications that dry up the oil and/or promote skin peeling may contain benzoyl peroxide, sulfur
resorcinol, salicylic acid or tretinoin, or retinoic acid (Retin-A)
Antibiotics (such as tetracycline or erythromycin) may be prescribed if the skin lesions appear infected. Topical 
antibiotics such (applied to a localized area of the skin) such as clindamycin or erythromycin are also used to 
control infection. 
Synthetic vitamin A analogues (isotretinoin, Accutane) have been shown to be of benefit in the treatment of 
severe acne. However, pregnant women should not take oral (by mouth) acne medications! 
Other medications may include topical or injected forms of cortisone
Surgical intervention may include professional (chemical) skin peeling, removal of eruptions or scars 
(dermabrasion), or removal and/or drainage of cysts
A small amount of sun exposure may improve acne. However, excessive exposure to sunlight or ultraviolet rays 
is not recommended because prolonged exposure increases the risk of skin cancer
Home treatment may lessen the effects of acne: 
- Clean the skin gently but thoroughly with soap and water, removing all dirt or make-up. Wash as often as 
needed to control oil, at least daily and after exercising. Use a clean washcloth every day to prevent bacterial 
reinfection. 
- Use steam or warm, moist compresses to open clogged pores. 
- Shampoo hair at least twice a week. Use a dandruff shampoo if necessary. 
- Comb or pull hair back to keep hair out of the face. 
- Use topical astringents to remove excess oil. 
- Don't squeeze, scratch, pick, or rub lesions. These activities can increase skin damage. Wash your hands before 
and after caring for skin lesions to reduce the chance of infection. 
- Don't rest your face on your hands. This irritates the skin of the face. 
- Identify and avoid anything that aggravates acne. This may include foods, lotions, make-up, and so on. Avoid 
greasy cosmetics or creams, which can aggravate acne. 
- Acne often improves in the summer, so some foods that aggravate acne may be tolerated in the summer but not 
in the winter. 
 
EXPECTATIONS (PROGNOSIS) 
Acne is usually chronic from puberty to adulthood, but eventually lessens. Acne generally responds well to 
treatment after a few weeks, but may flare up from time to time. Acne is not medically dangerous except for 
untreated, severe infection. 
 
COMPLICATIONS 
- cyst 
- skin abscess 
- permanent facial scars 
- keloids 
- skin pigment changes 
- psychological damage to self-esteem, confidence, personality, social life 
- side effects of Accutane (including liver damage and damage to the fetus) 
- side effects of other medications 
 
CALL YOUR HEALTH PROVIDER IF 
Apply home treatment and call your health care provider if there are signs of complications or if acne is severe 
and progressively worsening. 
Call for an appointment with your health care provider if new symptoms develop, including large or painful cysts