TAILEM BEND PHARMACY  
& KAROONDA PHARMACY DEPOT
 
Disease: Superficial Thrombophlebitis               PREVIOUS PAGE     
ALTERNATIVE NAMES 
phlebitis; thrombophlebitis 
 
DEFINITION 
An inflammation of a vein just below the surface of the skin, which results from a blood clot
 
CAUSES, INCIDENCE, AND RISK FACTORS 
Superficial thrombophlebitis may occur after recently using a intravenous (IV) line, or after trauma to the vein. It 
involves an inflammatory response associated with a clot in the vein. 
Risks include an increased blood clotting tendency, infection, current or recent pregnancy, varicose veins, and 
chemical or other irritation of the area. Prolonged sitting, standing, or immobilization increase the risk. Superficial 
thrombophlebitis may occasionally be associated with abdominal cancers (such as carcinoma of the pancreas)
deep vein thrombosis , thromboangiitis obliterans, and (rarely) with pulmonary embolus
 
PREVENTION 
If an intravenous line is in use, the risk of superficial thrombophlebitis may be reduced by frequent observation 
of the injection site, removal if signs of inflammation develop, and routine IV site rotation. 
 
SYMPTOMS 
- skin redness or inflammation along a superficial (skin) vein 
- redness of the tissue around a superficial vein 
- warmth of tissue around a superficial vein 
- tenderness or pain along a superficial vein, worse when pressure is applied over the vein 
- hardening of a superficial vein (induration) 
- vein feeling cord-like 
- leg pain 
 
SIGNS AND TESTS 
The health care provider makes the diagnosis of superficial thrombophlebitis primarily based on the appearance 
of the extremity. Frequent checks of the pulse, blood pressure, temperature, skin condition, and circulation may 
be required. 
If the cause is not readily identifiable, tests may be performed to determine the cause, including: 
- Doppler ultrasound 
- extremity arteriography 
Cultures of the skin or intravenous site drainage, or blood cultures, may be performed if infection is suspected. 
This disease may also alter the results of the following tests: 
- blood flow studies 
- antithrombin III 
 
TREATMENT 
The goal of treatment is reduction of inflammation. 
The intravenous catheter should be removed. 
Medications may include analgesics for pain, anticoagulants to prevent clot formation, thrombolytics to dissolve 
an existing clot, or others. Nonsteroidal antiinflammatory medication (NSAIDs) may reduce pain and 
inflammation. Antibiotics are prescribed if infection is present. 
Support stockings and wraps may be of benefit in reducing discomfort. Elevate the extremity to reduce swelling
Keep pressure off of it to reduce pain and decrease the risk of further damage. Apply moist heat to the extremity 
to reduce inflammation and pain. 
Surgical removal, stripping, or bypass of the vein is rarely needed, but it may be recommended in some situations. 
 
EXPECTATIONS (PROGNOSIS) 
Superficial thrombophlebitis is usually a benign and short term condition. Symptoms generally subside in 1 to 2 
weeks, but hardness of the vein may remain for much longer. 
 
COMPLICATIONS 
- infections (cellulitis) 
- gangrene (tissue death) 
- septic shock 
- deep vein thrombosis 
Note: Complications are rare. 
 
CALL YOUR HEALTH PROVIDER IF 
Call for an appointment with your health care provider if symptoms indicate superficial thrombophlebitis may be 
present. 
Call your health care provider if superficial thrombophlebitis has been diagnosed and symptoms do not improve 
with treatment or symptoms worsen, or if new symptoms occur, such as entire limb becoming pale, cold, or 
swollen, or if chills and fever develop.